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Analysis of the Association between CIMP and BRAF(V600E) in Colorectal Cancer by DNA Methylation Profiling
A CpG island methylator phenotype (CIMP) is displayed by a distinct subset of colorectal cancers with a high frequency of DNA hypermethylation in a specific group of CpG islands. Recent studies have shown that an activating mutation of BRAF (BRAF(V600E)) is tightly associated with CIMP, raising the...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2791229/ https://ncbi.nlm.nih.gov/pubmed/20027224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008357 |
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