CpG island methylator phenotype (CIMP) of colorectal cancer is best characterised by quantitative DNA methylation analysis and prospective cohort studies

BACKGROUND: The concept of CpG island methylator phenotype (CIMP) is not universally accepted. Even if specific clinicopathological features have been associated with CIMP, investigators often failed to demonstrate a bimodal distribution of the number of methylated markers, which would suggest CIMP...

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Detalhes bibliográficos
Main Authors: Ogino, S, Cantor, M, Kawasaki, T, Brahmandam, M, Kirkner, G J, Weisenberger, D J, Campan, M, Laird, P W, Loda, M, Fuchs, C S
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2006
Assuntos:
Gastrointestinal Cancer
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1856352/
https://ncbi.nlm.nih.gov/pubmed/16407376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2005.082933
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