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Androgen receptor signaling in circulating tumor cells as a marker of hormonally responsive prostate cancer

Androgen deprivation therapy (ADT) is initially effective in treating metastatic prostate cancer, and secondary hormonal therapies are being tested to suppress androgen receptor (AR) reactivation in castration-resistant prostate cancer (CRPC). Despite variable responses to AR pathway inhibitors in C...

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Autors principals: Miyamoto, David T., Lee, Richard J., Stott, Shannon L., Ting, David T., Wittner, Ben S., Ulman, Matthew, Smas, Malgorzata E., Lord, Jenna B., Brannigan, Brian W., Trautwein, Julie, Bander, Neil H., Wu, Chin-Lee, Sequist, Lecia V., Smith, Matthew R., Ramaswamy, Sridhar, Toner, Mehmet, Maheswaran, Shyamala, Haber, Daniel A.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508523/
https://ncbi.nlm.nih.gov/pubmed/23093251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-12-0222
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