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Transcription activator-like effector hybrids for conditional control and rewiring of chromosomal transgene expression
The ability to conditionally rewire pathways in human cells holds great therapeutic potential. Transcription activator-like effectors (TALEs) are a class of naturally occurring specific DNA binding proteins that can be used to introduce targeted genome modifications or control gene expression. Here...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3508452/ https://ncbi.nlm.nih.gov/pubmed/23193439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00897 |
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