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Assembly and Validation of Versatile Transcription Activator-Like Effector Libraries

The ability to perturb individual genes in genome-wide experiments has been instrumental in unraveling cellular and disease properties. Here we introduce, describe the assembly, and demonstrate the use of comprehensive and versatile transcription activator-like effector (TALE) libraries. As a proof...

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Bibliografiske detaljer
Main Authors: Li, Yi, Ehrhardt, Kristina, Zhang, Michael Q., Bleris, Leonidas
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010924/
https://ncbi.nlm.nih.gov/pubmed/24798576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04857
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