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Visualization of repetitive DNA sequences in human chromosomes with transcription activator-like effectors

We describe a transcription activator-like effector (TALE)-based strategy, termed “TALEColor,” for labeling specific repetitive DNA sequences in human chromosomes. We designed TALEs for the human telomeric repeat and fused them with any of numerous fluorescent proteins (FPs). Expression of these TAL...

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Detalhes bibliográficos
Main Authors: Ma, Hanhui, Reyes-Gutierrez, Pablo, Pederson, Thoru
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876203/
https://ncbi.nlm.nih.gov/pubmed/24324157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319097110
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