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Visualization of repetitive DNA sequences in human chromosomes with transcription activator-like effectors

We describe a transcription activator-like effector (TALE)-based strategy, termed “TALEColor,” for labeling specific repetitive DNA sequences in human chromosomes. We designed TALEs for the human telomeric repeat and fused them with any of numerous fluorescent proteins (FPs). Expression of these TAL...

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Bibliografiske detaljer
Main Authors: Ma, Hanhui, Reyes-Gutierrez, Pablo, Pederson, Thoru
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876203/
https://ncbi.nlm.nih.gov/pubmed/24324157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319097110
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