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Visualization of repetitive DNA sequences in human chromosomes with transcription activator-like effectors

We describe a transcription activator-like effector (TALE)-based strategy, termed “TALEColor,” for labeling specific repetitive DNA sequences in human chromosomes. We designed TALEs for the human telomeric repeat and fused them with any of numerous fluorescent proteins (FPs). Expression of these TAL...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ma, Hanhui, Reyes-Gutierrez, Pablo, Pederson, Thoru
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876203/
https://ncbi.nlm.nih.gov/pubmed/24324157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319097110
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