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Amyloid plaque formation precedes dendritic spine loss
Amyloid-beta plaque deposition represents a major neuropathological hallmark of Alzheimer’s disease. While numerous studies have described dendritic spine loss in proximity to plaques, much less is known about the kinetics of these processes. In particular, the question as to whether synapse loss pr...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3508278/ https://ncbi.nlm.nih.gov/pubmed/22993126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-012-1047-8 |
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