Amyloid plaque formation precedes dendritic spine loss

Amyloid-beta plaque deposition represents a major neuropathological hallmark of Alzheimer’s disease. While numerous studies have described dendritic spine loss in proximity to plaques, much less is known about the kinetics of these processes. In particular, the question as to whether synapse loss pr...

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Bibliografiske detaljer
Main Authors: Bittner, Tobias, Burgold, Steffen, Dorostkar, Mario M., Fuhrmann, Martin, Wegenast-Braun, Bettina M., Schmidt, Boris, Kretzschmar, Hans, Herms, Jochen
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2012
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Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508278/
https://ncbi.nlm.nih.gov/pubmed/22993126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-012-1047-8
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