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Intravital Fluorescence Imaging of Small Interfering RNA–Mediated Gene Repression in a Dual Reporter Melanoma Xenograft Model
Development of RNA interference (RNAi)-based therapeutics has been hampered by the lack of effective and efficient means of delivery. Reliable model systems for screening and optimizing delivery of RNAi-based agents in vivo are crucial for preclinical research aimed at advancing nucleic acid-based t...
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Главные авторы: | , , , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
Mary Ann Liebert, Inc.
2012
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3507521/ https://ncbi.nlm.nih.gov/pubmed/23098239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2012.0364 |
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