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Intravital Fluorescence Imaging of Small Interfering RNA–Mediated Gene Repression in a Dual Reporter Melanoma Xenograft Model

Development of RNA interference (RNAi)-based therapeutics has been hampered by the lack of effective and efficient means of delivery. Reliable model systems for screening and optimizing delivery of RNAi-based agents in vivo are crucial for preclinical research aimed at advancing nucleic acid-based t...

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Библиографические подробности
Главные авторы: Hickerson, Robyn P., Gonzalez-Gonzalez, Emilio, Vlassov, Alexander V., Li, Mu, Lara, Maria Fernanda, Contag, Christopher H., Kaspar, Roger L.
Формат: Artigo
Язык:Inglês
Опубликовано: Mary Ann Liebert, Inc. 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507521/
https://ncbi.nlm.nih.gov/pubmed/23098239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2012.0364
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