CDK inhibitors R-roscovitine and S-CR8 effectively block renal and hepatic cystogenesis in an orthologous model of ADPKD

Autosomal dominant polycystic kidney disease (ADPKD) and other forms of PKD are associated with dysregulated cell cycle and proliferation. Although no effective therapy for the treatment of PKD is currently available, possible mechanism-based approaches are beginning to emerge. A therapeutic interve...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Bukanov, Nikolay O., Moreno, Sarah E., Natoli, Thomas A., Rogers, Kelly A., Smith, Laurie A., Ledbetter, Steven R., Oumata, Nassima, Galons, Hervé, Meijer, Laurent, Ibraghimov-Beskrovnaya, Oxana
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2012
Materias:
Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507499/
https://ncbi.nlm.nih.gov/pubmed/23032260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.22375
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares