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Cyclosporin A inhibits colon cancer cell growth independently of the calcineurin pathway

Chronic inflammation is a risk factor for the development of colon cancer, providing genotoxic insults, growth and pro-angiogenic factors that can promote tumorigenesis and tumor growth. Immunomodulatory agents can interfere with the inflammation that feeds cancer, but their impact on the transforme...

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Detalhes bibliográficos
Main Authors: Werneck, Miriam B.F., Hottz, Eugênio, Bozza, Patrícia T., Viola, João P.B.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507495/
https://ncbi.nlm.nih.gov/pubmed/22992618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.22222
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