A Calcineurin-Independent Mechanism of Angiogenesis Inhibition by a Nonimmunosuppressive Cyclosporin A Analog

Cyclosporin A (CsA) is a widely used immunosuppressant drug. Its immunosuppressive activity occurs through the inhibition of the protein phosphatase calcineurin via formation of a ternary complex with cyclophilin A (CypA). CsA also inhibits endothelial cell proliferation and angiogenesis. This has b...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Nacev, Benjamin A., Low, Woon-Kai, Huang, Zhennian, Su, Tina T., Su, Zhuang, Alkuraya, Hisham, Kasuga, Dan, Sun, Woong, Träger, Mario, Braun, Manfred, Fischer, Gunter, Zhang, Kang, Liu, Jun O.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Pharmacology and Experimental Therapeutics 2011
Teme:
Chemotherapy, Antibiotics, and Gene Therapy
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141903/
https://ncbi.nlm.nih.gov/pubmed/21562139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.180851
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki