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Inhibition of human immunodeficiency virus replication by nonimmunosuppressive analogs of cyclosporin A.

Analogs of the immunosuppressive cyclic undecapeptide cyclosporin A (CsA) with substitutions in positions 1, 4, 6, and/or 11 were rationally designed to possess substantially diminished or no immunosuppressive activity. When these compounds were assayed for their capacity to interfere with the repli...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Bartz, S R, Hohenwalter, E, Hu, M K, Rich, D H, Malkovsky, M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41698/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7777516/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.12.5381
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