Specific inhibition of human immunodeficiency virus type 1 replication by antisense oligonucleotides: an in vitro model for treatment.

We have developed a culture system, simulating in vivo conditions of human immunodeficiency virus type 1 (HIV-1) infection, to evaluate the long-term efficacy of antisense oligonucleotide treatment. Five oligonucleotide phosphorothioates (28-mers), complementary to different regions of HIV-1 RNA, bl...

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Bibliografiska uppgifter
Huvudupphovsmän: Lisziewicz, J, Sun, D, Klotman, M, Agrawal, S, Zamecnik, P, Gallo, R
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1992
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC50519/
https://ncbi.nlm.nih.gov/pubmed/1454800
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