Potent inhibition of human immunodeficiency virus type 1 replication by an intracellular anti-Rev single-chain antibody.

Human immunodeficiency virus type 1 (HIV-1) has a complex life cycle, which has made it a difficult target for conventional therapeutic modalities. A single-chain antibody moiety, directed against the HIV-1 regulatory protein Rev, which rescues unspliced viral RNA from the nucleus of infected cells,...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Duan, L, Bagasra, O, Laughlin, M A, Oakes, J W, Pomerantz, R J
Format: Artigo
Langue:Inglês
Publié: 1994
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC43934/
https://ncbi.nlm.nih.gov/pubmed/8197188
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