Transgenic mice expressing human CD14 are hypersensitive to lipopolysaccharide.

In vitro studies have previously shown that the myelomonocytic differentiation antigen CD14 is a receptor for a complex consisting of lipopolysaccharide (LPS) and LPS-binding protein. To investigate the role of CD14 in vivo and its relationship to induction of LPS-induced endotoxin shock, transgenic...

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Detalles Bibliográficos
Main Authors: Ferrero, E, Jiao, D, Tsuberi, B Z, Tesio, L, Rong, G W, Haziot, A, Goyert, S M
Formato: Artigo
Idioma:Inglês
Publicado: 1993
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC46090/
https://ncbi.nlm.nih.gov/pubmed/7681594
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