Transgenic mice expressing human CD14 are hypersensitive to lipopolysaccharide.

In vitro studies have previously shown that the myelomonocytic differentiation antigen CD14 is a receptor for a complex consisting of lipopolysaccharide (LPS) and LPS-binding protein. To investigate the role of CD14 in vivo and its relationship to induction of LPS-induced endotoxin shock, transgenic...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Ferrero, E, Jiao, D, Tsuberi, B Z, Tesio, L, Rong, G W, Haziot, A, Goyert, S M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46090/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7681594/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.6.2380
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