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Hypoxia and gerosuppression: The mTOR saga continues
Growth-promoting and nutrient/mitogen-sensing pathways such as mTOR convert p21- and p16-induced arrest into senescence (geroconversion). We have recently demonstrated that hypoxia, especially near-anoxia, suppresses geroconversion. This gerosuppressive effect of hypoxia correlated with inhibition o...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Landes Bioscience
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3507487/ https://ncbi.nlm.nih.gov/pubmed/22987149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21908 |
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