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Notch ligand endocytosis: Mechanistic basis of signaling activity

Regulation of Notch signaling is critical to development and maintenance of most eukaryotic organisms. The Notch receptors and ligands are integral membrane proteins and direct cell–cell interactions are needed to activate signaling. Ligand-expressing cells activate Notch signaling through an unusua...

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Detalhes bibliográficos
Main Authors: Musse, Abdiwahab A., Meloty-Kapella, Laurence, Weinmaster, Gerry
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507467/
https://ncbi.nlm.nih.gov/pubmed/22306180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2012.01.011
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