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Notch Ligand Endocytosis Generates Mechanical Pulling Force Dependent on Dynamin, Epsins and Actin

Notch signaling induced by cell surface ligands is critical to development and maintenance of many eukaryotic organisms. Notch and its ligands are integral membrane proteins that facilitate direct cell-cell interactions to activate Notch proteolysis and release the intracellular domain that directs...

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Hlavní autoři: Meloty-Kapella, Laurence, Shergill, Bhupinder, Kuon, Jane, Botvinick, Elliot, Weinmaster, Gerry
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400432/
https://ncbi.nlm.nih.gov/pubmed/22658936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.04.005
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