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Notch Ligand Ubiquitylation: What Is It Good For?

In the first volume of Developmental Cell, it was reported that the classic Drosophila neurogenic gene neuralized encodes a ubiquitin ligase that monoubiquitylates the Notch ligand Delta, thus promoting Delta endocytosis. A requirement for ligand internalization by the signal-sending cell, although...

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Detalhes bibliográficos
Main Authors: Weinmaster, Gerry, Fischer, Janice A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156059/
https://ncbi.nlm.nih.gov/pubmed/21763614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.06.006
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