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A role for Rap2 in recycling the extended conformation of LFA-1 during T cell migration

T lymphocytes make use of their major integrin LFA-1 to migrate on surfaces that express ICAM-1 such as blood vessels and inflamed tissue sites. How the adhesions are turned over in order to supply traction for this migration has not been extensively investigated. By following the fate of biotinylat...

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Detalhes bibliográficos
Main Authors: Stanley, Paula, Tooze, Sharon, Hogg, Nancy
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507183/
https://ncbi.nlm.nih.gov/pubmed/23213397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20122824
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