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The Gαq/11 Proteins Contribute to T Lymphocyte Migration by Promoting Turnover of Integrin LFA-1 through Recycling

The role of Gαi proteins coupled to chemokine receptors in directed migration of immune cells is well understood. In this study we show that the separate class of Gαq/11 proteins is required for the underlying ability of T cells to migrate both randomly and in a directed chemokine-dependent manner....

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מידע ביבליוגרפי
Main Authors: Svensson, Lena, Stanley, Paula, Willenbrock, Frances, Hogg, Nancy
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372505/
https://ncbi.nlm.nih.gov/pubmed/22701657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038517
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