Purified Clostridium difficile cytotoxin stimulates guanylate cyclase activity and inhibits adenylate cyclase activity.

Antibiotic-associated pseudomembranous colitis has been linked with Clostridium difficile toxin. We examined the effect of toxins from four strains of C. difficile isolated from patients with pseudomembranous colitis on colonic adenylate (EC 4.6.1.1) and guanylate cyclase (EC 4.6.1.2) activities. Pa...

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Détails bibliographiques
Auteurs principaux: Vesely, D L, Straub, K D, Nolan, C M, Rolfe, R D, Finegold, S M, Monson, T P
Format: Artigo
Langue:Inglês
Publié: 1981
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC350687/
https://ncbi.nlm.nih.gov/pubmed/6114928
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