Purified Clostridium difficile cytotoxin stimulates guanylate cyclase activity and inhibits adenylate cyclase activity.

Antibiotic-associated pseudomembranous colitis has been linked with Clostridium difficile toxin. We examined the effect of toxins from four strains of C. difficile isolated from patients with pseudomembranous colitis on colonic adenylate (EC 4.6.1.1) and guanylate cyclase (EC 4.6.1.2) activities. Pa...

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Vydáno v:	Infect Immun
Hlavní autoři:	Vesely, D L, Straub, K D, Nolan, C M, Rolfe, R D, Finegold, S M, Monson, T P
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1981
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350687/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6114928/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.33.1.285-291.1981
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