Purified Clostridium difficile cytotoxin stimulates guanylate cyclase activity and inhibits adenylate cyclase activity.

Antibiotic-associated pseudomembranous colitis has been linked with Clostridium difficile toxin. We examined the effect of toxins from four strains of C. difficile isolated from patients with pseudomembranous colitis on colonic adenylate (EC 4.6.1.1) and guanylate cyclase (EC 4.6.1.2) activities. Pa...

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Autores principales: Vesely, D L, Straub, K D, Nolan, C M, Rolfe, R D, Finegold, S M, Monson, T P
Formato: Artigo
Lenguaje:Inglês
Publicado: 1981
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC350687/
https://ncbi.nlm.nih.gov/pubmed/6114928
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