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Purified Clostridium difficile cytotoxin stimulates guanylate cyclase activity and inhibits adenylate cyclase activity.

Antibiotic-associated pseudomembranous colitis has been linked with Clostridium difficile toxin. We examined the effect of toxins from four strains of C. difficile isolated from patients with pseudomembranous colitis on colonic adenylate (EC 4.6.1.1) and guanylate cyclase (EC 4.6.1.2) activities. Pa...

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書誌詳細
出版年:Infect Immun
主要な著者: Vesely, D L, Straub, K D, Nolan, C M, Rolfe, R D, Finegold, S M, Monson, T P
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1981
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350687/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6114928/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.33.1.285-291.1981
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