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Evidence for a thermodynamically distinct Mg(2+) ion associated with formation of an RNA tertiary structure

A folding strategy adopted by some RNAs is to chelate cations in pockets or cavities, where the ions neutralize charge from solvent-inaccessible phosphate. Although such buried Mg(2+)-RNA chelates could be responsible for a significant fraction of the Mg(2+)-dependent stabilization free energy of so...

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Detalhes bibliográficos
Main Authors: Leipply, Desirae, Draper, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505420/
https://ncbi.nlm.nih.gov/pubmed/21776997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2020923
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