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Evidence for a thermodynamically distinct Mg(2+) ion associated with formation of an RNA tertiary structure
A folding strategy adopted by some RNAs is to chelate cations in pockets or cavities, where the ions neutralize charge from solvent-inaccessible phosphate. Although such buried Mg(2+)-RNA chelates could be responsible for a significant fraction of the Mg(2+)-dependent stabilization free energy of so...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3505420/ https://ncbi.nlm.nih.gov/pubmed/21776997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2020923 |
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