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The dependence of RNA tertiary structure stability on Mg(2+) concentration: interpretation of the Hill equation and coefficient
The Mg(2+)-induced folding of RNA tertiary structures is readily observed via titrations of RNA with MgCl(2). Such titrations are commonly analyzed using a site-binding formalism that includes a parameter, the Hill coefficient n, which is sometimes deemed the number of Mg(2+) ions bound by the nativ...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3001042/ https://ncbi.nlm.nih.gov/pubmed/20112919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi902036j |
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