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The dependence of RNA tertiary structure stability on Mg(2+) concentration: interpretation of the Hill equation and coefficient

The Mg(2+)-induced folding of RNA tertiary structures is readily observed via titrations of RNA with MgCl(2). Such titrations are commonly analyzed using a site-binding formalism that includes a parameter, the Hill coefficient n, which is sometimes deemed the number of Mg(2+) ions bound by the nativ...

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Detalhes bibliográficos
Main Authors: Leipply, Desirae, Draper, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001042/
https://ncbi.nlm.nih.gov/pubmed/20112919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi902036j
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