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Cyclization of Fungal Nonribosomal Peptides by a Terminal Condensation-Like Domain
Cyclization of linear peptidyl precursors produced by nonribosomal peptide synthetases (NRPSs) is an important step in the biosynthesis of bioactive cyclic peptides. Whereas bacterial NRPSs use thioesterase (TE) domains to perform the cyclization, fungal NRPSs have apparently evolved to use a differ...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3505271/ https://ncbi.nlm.nih.gov/pubmed/22902615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1047 |
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