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Cyclization of Fungal Nonribosomal Peptides by a Terminal Condensation-Like Domain

Cyclization of linear peptidyl precursors produced by nonribosomal peptide synthetases (NRPSs) is an important step in the biosynthesis of bioactive cyclic peptides. Whereas bacterial NRPSs use thioesterase (TE) domains to perform the cyclization, fungal NRPSs have apparently evolved to use a differ...

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Bibliografische gegevens
Hoofdauteurs: Gao, Xue, Haynes, Stuart W., Ames, Brian D., Wang, Peng, Vien, Linda P., Walsh, Christopher T., Tang, Yi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505271/
https://ncbi.nlm.nih.gov/pubmed/22902615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1047
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