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Cyclization of Fungal Nonribosomal Peptides by a Terminal Condensation-Like Domain

Cyclization of linear peptidyl precursors produced by nonribosomal peptide synthetases (NRPSs) is an important step in the biosynthesis of bioactive cyclic peptides. Whereas bacterial NRPSs use thioesterase (TE) domains to perform the cyclization, fungal NRPSs have apparently evolved to use a differ...

詳細記述

保存先:
書誌詳細
主要な著者: Gao, Xue, Haynes, Stuart W., Ames, Brian D., Wang, Peng, Vien, Linda P., Walsh, Christopher T., Tang, Yi
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505271/
https://ncbi.nlm.nih.gov/pubmed/22902615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1047
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