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Cyclization of Fungal Nonribosomal Peptides by a Terminal Condensation-Like Domain

Cyclization of linear peptidyl precursors produced by nonribosomal peptide synthetases (NRPSs) is an important step in the biosynthesis of bioactive cyclic peptides. Whereas bacterial NRPSs use thioesterase (TE) domains to perform the cyclization, fungal NRPSs have apparently evolved to use a differ...

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Bibliografiset tiedot
Päätekijät: Gao, Xue, Haynes, Stuart W., Ames, Brian D., Wang, Peng, Vien, Linda P., Walsh, Christopher T., Tang, Yi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505271/
https://ncbi.nlm.nih.gov/pubmed/22902615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1047
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