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Unraveling terminal C-domain-mediated condensation in fungal biosynthesis of imidazoindolone metabolites()

The fungal peptidyl alkaloids of the tryptoquialanine and fumiquinazoline families are nonribosomally assembled by annulation of the indole side chain of fumiquinazoloine F (FQF) with an alaninyl or aminoisobutyryl unit by monomodular NRPS enzymes containing adenylation, thiolation and condensation...

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Detalhes bibliográficos
Main Authors: Haynes, Stuart W., Ames, Brian D., Gao, Xue, Tang, Yi, Walsh, Christopher T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119741/
https://ncbi.nlm.nih.gov/pubmed/21591693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2004922
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