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Sloppy Models, Parameter Uncertainty, and the Role of Experimental Design
Computational models are increasingly used to understand and predict complex biological phenomena. These models contain many unknown parameters, at least some of which are difficult to measure directly, and instead are estimated by fitting to time-course data. Previous work has suggested that even w...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3505121/ https://ncbi.nlm.nih.gov/pubmed/20556289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b918098b |
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