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Stimulus Design for Model Selection and Validation in Cell Signaling

Mechanism-based chemical kinetic models are increasingly being used to describe biological signaling. Such models serve to encapsulate current understanding of pathways and to enable insight into complex biological processes. One challenge in model development is that, with limited experimental data...

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Detalhes bibliográficos
Main Authors: Apgar, Joshua F, Toettcher, Jared E, Endy, Drew, White, Forest M, Tidor, Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323406/
https://ncbi.nlm.nih.gov/pubmed/18282085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0040030
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