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Dual Specificity Phosphatase 4 Mediates Cardiomyopathy Caused by Lamin A/C (LMNA) Gene Mutation

Mutations in the lamin A/C gene (LMNA) cause a diverse spectrum of diseases, the most common of which is dilated cardiomyopathy often with skeletal muscular dystrophy. Lamin A and C are fundamental components of the nuclear lamina, a dynamic meshwork of intermediate filaments lining the nuclear enve...

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Autors principals: Choi, Jason C., Wu, Wei, Muchir, Antoine, Iwata, Shinichi, Homma, Shunichi, Worman, Howard J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504766/
https://ncbi.nlm.nih.gov/pubmed/23048029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.404541
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