Loss of naïve T-cells and repertoire constriction predict poor response to vaccination in old primates

Aging is usually accompanied by diminished immune protection upon infection or vaccination. While aging results in well-characterized changes in the T-cell compartment of long-lived, outbred, and pathogen-exposed organisms, their relevance for primary antigen responses remain unclear. Therefore, it...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Čičin-Šain, Luka, Smyk-Paerson, Sue, Currier, Noreen, Byrd, Laura, Koudelka, Caroline, Robinson, Tammie, Swarbrick, Gwendolyn, Tackitt, Shane, Legasse, Alfred, Fischer, Miranda, Nikolich-Zugich, Dragana, Park, Byung, Hobbs, Theodore, Doane, Cynthia J., Mori, Motomi, Axthelm, Michael T., Lewinsohn, Deborah A., Nikolich-Žugich, Janko
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504654/
https://ncbi.nlm.nih.gov/pubmed/20483749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0904193
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak