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Cytomegalovirus Infection Impairs Immune Responses and Accentuates T-cell Pool Changes Observed in Mice with Aging

Prominent immune alterations associated with aging include the loss of naïve T-cell numbers, diversity and function. While genetic contributors and mechanistic details in the aging process have been addressed in multiple studies, the role of environmental agents in immune aging remains incompletely...

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Detalhes bibliográficos
Main Authors: Cicin-Sain, Luka, Brien, James D., Uhrlaub, Jennifer L., Drabig, Anja, Marandu, Thomas F., Nikolich-Zugich, Janko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420928/
https://ncbi.nlm.nih.gov/pubmed/22916012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002849
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