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Cytomegalovirus Infection Impairs Immune Responses and Accentuates T-cell Pool Changes Observed in Mice with Aging

Prominent immune alterations associated with aging include the loss of naïve T-cell numbers, diversity and function. While genetic contributors and mechanistic details in the aging process have been addressed in multiple studies, the role of environmental agents in immune aging remains incompletely...

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Autors principals: Cicin-Sain, Luka, Brien, James D., Uhrlaub, Jennifer L., Drabig, Anja, Marandu, Thomas F., Nikolich-Zugich, Janko
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420928/
https://ncbi.nlm.nih.gov/pubmed/22916012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002849
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