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Alcohol-Induced Modulation of Rictor and mTORC2 Activity in C2C12 Myoblasts
BACKGROUND: The mTOR kinase controls cell growth, proliferation and metabolism through two distinct multi-protein complexes, mTORC1 and mTORC2. We reported that alcohol (EtOH) inhibits mTORC1 activity and protein synthesis in C2C12 myoblasts. However, the role that mTORC2 plays in this process has n...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3503252/ https://ncbi.nlm.nih.gov/pubmed/21438886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2011.01480.x |
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