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Alcohol-Induced Modulation of Rictor and mTORC2 Activity in C2C12 Myoblasts

BACKGROUND: The mTOR kinase controls cell growth, proliferation and metabolism through two distinct multi-protein complexes, mTORC1 and mTORC2. We reported that alcohol (EtOH) inhibits mTORC1 activity and protein synthesis in C2C12 myoblasts. However, the role that mTORC2 plays in this process has n...

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Detalhes bibliográficos
Main Authors: Hong-Brown, Ly Q., Brown, C. Randell, Navaratnarajah, Maithili, Huber, Danuta S., Lang, Charles H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503252/
https://ncbi.nlm.nih.gov/pubmed/21438886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2011.01480.x
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