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The mTORC2 Complex Regulates Terminal Differentiation of C2C12 Myoblasts
Rapamycin, a selective inhibitor of mTORC1 signaling, blocks terminal myoblast differentiation. We found that downregulation of rictor, a component of the mTORC2 complex, but not downregulation of raptor, a component of the mTORC1 complex, prevented terminal differentiation (fusion) of C2C12 myoblas...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2725723/ https://ncbi.nlm.nih.gov/pubmed/19564418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00764-09 |
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