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Capturing native long-range contiguity by in situ library construction and optical sequencing

The relatively short read lengths associated with the most cost-effective DNA sequencing technologies have limited their use in de novo genome assembly, structural variation detection, and haplotype-resolved genome sequencing. Consequently, there is a strong need for methods that capture various sca...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Schwartz, Jerrod J., Lee, Choli, Hiatt, Joseph B., Adey, Andrew, Shendure, Jay
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503199/
https://ncbi.nlm.nih.gov/pubmed/23112150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1202680109
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