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Capturing native long-range contiguity by in situ library construction and optical sequencing

The relatively short read lengths associated with the most cost-effective DNA sequencing technologies have limited their use in de novo genome assembly, structural variation detection, and haplotype-resolved genome sequencing. Consequently, there is a strong need for methods that capture various sca...

詳細記述

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書誌詳細
主要な著者: Schwartz, Jerrod J., Lee, Choli, Hiatt, Joseph B., Adey, Andrew, Shendure, Jay
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503199/
https://ncbi.nlm.nih.gov/pubmed/23112150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1202680109
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