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Capturing native long-range contiguity by in situ library construction and optical sequencing
The relatively short read lengths associated with the most cost-effective DNA sequencing technologies have limited their use in de novo genome assembly, structural variation detection, and haplotype-resolved genome sequencing. Consequently, there is a strong need for methods that capture various sca...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3503199/ https://ncbi.nlm.nih.gov/pubmed/23112150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1202680109 |
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