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UCP3 Regulates Cardiac Efficiency and Mitochondrial Coupling in High Fat–Fed Mice but Not in Leptin-Deficient Mice

These studies investigate the role of uncoupling protein 3 (UCP3) in cardiac energy metabolism, cardiac O(2) consumption (MVO(2)), cardiac efficiency (CE), and mitochondrial uncoupling in high fat (HF)–fed or leptin-deficient mice. UCP3KO and wild-type (WT) mice were fed normal chow or HF diets for...

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Detalhes bibliográficos
Main Authors: Boudina, Sihem, Han, Yong Hwan, Pei, Shaobo, Tidwell, Timothy J., Henrie, Brandon, Tuinei, Joseph, Olsen, Curtis, Sena, Sandra, Abel, E. Dale
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501860/
https://ncbi.nlm.nih.gov/pubmed/22912419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0063
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