Epiregulin induces leptin secretion and energy expenditure in high-fat diet-fed mice

Adipokine leptin regulates neuroendocrine circuits that control energy expenditure, thermogenesis, and weight loss. However, canonic regulators of leptin secretion, such as insulin and malonyl CoA, do not support these processes. We hypothesize that epiregulin (EREG), a growth factor that is secrete...

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Veröffentlicht in:J Endocrinol
Hauptverfasser: Yasmeen, Rumana, Shen, Qiwen, Lee, Aejin, Leung, Jacob H., Kowdley, Devan, DiSilvestro, David J., Xu, Lu, Yang, Kefeng, Maiseyeu, Andrei, Bal, Naresh C., Periasamy, Muthu, Fadda, Paolo, Ziouzenkova, Ouliana
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6226053/
https://ncbi.nlm.nih.gov/pubmed/30400011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-18-0289
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