Epiregulin induces leptin secretion and energy expenditure in high-fat diet-fed mice

Adipokine leptin regulates neuroendocrine circuits that control energy expenditure, thermogenesis, and weight loss. However, canonic regulators of leptin secretion, such as insulin and malonyl CoA, do not support these processes. We hypothesize that epiregulin (EREG), a growth factor that is secrete...

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Pubblicato in:J Endocrinol
Autori principali: Yasmeen, Rumana, Shen, Qiwen, Lee, Aejin, Leung, Jacob H., Kowdley, Devan, DiSilvestro, David J., Xu, Lu, Yang, Kefeng, Maiseyeu, Andrei, Bal, Naresh C., Periasamy, Muthu, Fadda, Paolo, Ziouzenkova, Ouliana
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6226053/
https://ncbi.nlm.nih.gov/pubmed/30400011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-18-0289
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