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Sulforaphane improves leptin responsiveness in high-fat high-sucrose diet-fed obese mice

Diet-induced obesity (DIO) is commonly associated with hyperleptinemia and leptin resistance. Leptin acts centrally to inhibit food intake and increase energy expenditure, thereby preventing body weight gain. Resistance to the biological effects of leptin represents a major obstacle in utilizing exo...

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Publicado en:Eur J Pharmacol
Main Authors: Shawky, Noha M., Segar, Lakshman
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6110095/
https://ncbi.nlm.nih.gov/pubmed/30063917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2018.07.050
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