Genome-wide association study identifies germline polymorphisms associated with relapse of childhood acute lymphoblastic leukemia

With the use of risk-directed therapy for childhood acute lymphoblastic leukemia (ALL), outcome has improved dramatically in the past 40 years. However, a substantial portion of patients, many of whom have no known risk factors, experience relapse. Taking a genome-wide approach, in the present study...

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Autori principali: Yang, Jun J., Cheng, Cheng, Devidas, Meenakshi, Cao, Xueyuan, Campana, Dario, Yang, Wenjian, Fan, Yiping, Neale, Geoff, Cox, Nancy, Scheet, Paul, Borowitz, Michael J., Winick, Naomi J., Martin, Paul L., Bowman, W. Paul, Camitta, Bruce, Reaman, Gregory H., Carroll, William L., Willman, Cheryl L., Hunger, Stephen P., Evans, William E., Pui, Ching-Hon, Loh, Mignon, Relling, Mary V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2012
Soggetti:
Lymphoid Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501717/
https://ncbi.nlm.nih.gov/pubmed/23007406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-07-440107
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